SHS3 Biomedical Science · Semester 1 Week 20: Diseases and Disorders

Lesson notes

Learning Objectives

Indicator: 3.2.2.LI.2 - Explain how cholesterol is transported in the blood by high density lipoprotein (HDL) and low-density lipoprotein (LDL) and the role each of them plays in the body.

By the end of the lesson, learners can:

State why cholesterol cannot dissolve in blood on its own and must be carried by lipoproteins.
Distinguish between high density lipoprotein (HDL) and low density lipoprotein (LDL) in terms of structure, composition and density.
Explain the roles of LDL (delivering cholesterol to body cells) and HDL (returning excess cholesterol to the liver) in cholesterol transport.
Use a simple model or diagram to trace the journey of cholesterol from the liver to body cells and back.
Describe what the terms “good cholesterol” and “bad cholesterol” mean in everyday language, using accurate scientific reasoning.

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Curriculum details

Strand: Human Body Systems (Strand 2)
Sub-strand: Diseases and Disorders (2.2)
Content standard: 3.2.2.CS.1 - Demonstrate an understanding of the function of cholesterol in the body and its role in heart disease. 3.2.2.LO.1 Describe the different types of lipids in the body, explain how cholesterol-lipoprotein complexes affect risk of heart diseases and how risk of heart diseases may be assessed.
Indicator: 3.2.2.LI.2 - Explain how cholesterol is transported in the blood by high density lipoprotein (HDL) and low-density lipoprotein (LDL) and the role each of them plays in the body.
Suggested placement: Semester 1, Week 20 (Week 20 of the year)
Our suggestion, laid out in curriculum order across three terms of twelve weeks. NaCCA does not fix the week, so follow your school's scheme of learning.
Curriculum reference: NaCCA curriculum document, p. 92

Exemplars (from the NaCCA curriculum)

Talk for Learning: With the aid of charts, videos or information graphs, engage in a class discussion on why cholesterol is necessary in the body and how cholesterol is transported as lipoprotein-cholesterol.
Collaborative Learning: Learners work in mixed-ability groups to do a write-up on the differences between high density lipoprotein (HDL) and low-density lipoprotein (LDL) and their roles in the body and present to the class for comments.
Teaching and Learning Resources:
- Sticks and balls from local materials sketch boards or pads
- Internet
- Textbooks
- Writing board
- Projector
- Sample cholesterol measurement results
- Sample angiograms or images
Assessment (3.2.2.AS.2). The document marks these depth-of-knowledge levels for this indicator: Level 2 Skills of conceptual understanding; Level 4 Extended critical thinking and reasoning.